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Non-melanoma skin cancer (NMSC) remains a prevalent malignant neoplasm affecting the skin globally. Over the past 30 years, the prevalence and incidence of NMSC in China have notably evolved, while mortality rate (MR) data remains limited. Our intention is to analytically assess the MR data of NMSC patients across the globe from 1992 to 2021, examine its temporal trends, and offer significant epidemiological insights for future NMSC prevention and management strategies.

非黑色素瘤皮肤癌（NMSC）仍然是全球范围内影响皮肤的一种常见恶性肿瘤。在过去的30年中，中国NMSC的患病率和发病率显著变化，但死亡率（MR）数据仍然有限。我们的目的是分析评估1992年至2021年全球NMSC患者的MR数据，研究其时间趋势，并为未来NMSC的预防和管理策略提供重要的流行病学见解。

The data utilized originates from the Global Burden of Disease Study 2021 (GBD 2021) Data Resources. The MR for NMSC demonstrated a growing trend globally. From 1992 to 2021, both the crude mortality rate (CMR) and age-standardized mortality rate (ASMR) for NMSC saw substantial increases worldwide.Throughout this period, the global ASMR experienced a rise of roughly 30%.

所使用的数据来源于2021年全球疾病负担研究（GBD 2021）数据资源。非黑色素瘤皮肤癌（NMSC）的死亡率在全球范围内呈现增长趋势。从1992年到2021年，全球NMSC的粗死亡率（CMR）和年龄标准化死亡率（ASMR）均有显著增加。在此期间，全球ASMR上升了大约30%。

Males represented a higher ASMR compared to females. Lastly, the elderly population showed an accelerated and elevated ASMR for NMSC trend. There is a growing mortality for NMSC in China, with current male MR outpacing those of females. Despite a projected decline in ASMR by 2030, the number of mortality cases is anticipated to rise, particularly among males.

男性ASMR高于女性。最后，老年人群NMSC趋势的ASMR呈现加速上升。中国NMSC的死亡率不断上升，目前男性的MR已超过女性。尽管预计到2030年ASMR将下降，但死亡人数预计仍会上升，尤其是在男性中。

The MR for NMSC demonstrate a pronounced bias towards the elderly demographic. In addition to prevention and intervention measures in susceptible populations, it is crucial to establish a NMSC screening framework for detecting minor symptoms..

非黑色素瘤皮肤癌的死亡率显示出对老年人群的显著偏倚。除了在易感人群中采取预防和干预措施外，建立一个用于检测轻微症状的非黑色素瘤皮肤癌筛查框架也至关重要。