A clinical trial with People Science validates LP815's anxiety benefits and marks a major advance in gut-brain health.

一项与人科学的临床试验验证了LP815的抗焦虑益处，并标志着肠道-大脑健康领域的一项重大进展。

BOULDER, Colo.

博尔德，科罗拉多州

,

，

April 29, 2025

2025年4月29日

/PRNewswire/ -- Verb Biotics, in collaboration with leading

/PRNewswire/ -- Verb Biotics，与领先的机构合作

decentralized

去中心化的

clinical research organization People Science, announced promising results from a randomized, double-blind, placebo-controlled clinical trial demonstrating that daily supplementation with the GABA-producing probiotic strain

临床研究组织 People Science 宣布了一项随机、双盲、安慰剂对照临床试验的可喜结果，证明每日补充产 GABA 的益生菌菌株

Lactiplantibacillus plantarum,

植物乳杆菌，

LP815™, significantly reduced anxiety levels in adults with mild to moderate anxiety (

LP815™，显著降低了轻度至中度焦虑成年人的焦虑水平（

manuscript published in Beneficial Microbes

发表在《有益微生物》期刊的手稿

).

）。

The six-week study evaluated the effects of LP815™ compared to placebo on anxiety, mood, sleep, and quality of life. The trial drew a diverse group of participants, 63% of whom were women. Participants who received 5 billion CFU per day experienced a clinically meaningful reduction in anxiety, with 68% improving by more than one category on the GAD-7 anxiety scale by week six, compared to just 26% in the placebo group.

这项为期六周的研究评估了LP815™与安慰剂对焦虑、情绪、睡眠和生活质量的影响。试验吸引了一群多样化的参与者，其中63%是女性。每天摄入50亿CFU的参与者在焦虑方面经历了具有临床意义的减少，到第六周时，68%的参与者在GAD-7焦虑量表上改善了一个以上的类别，而安慰剂组中仅有26%的人有此改善。

The study, conducted through People Science's innovative digital clinical trial platform Chloe, reflects a broader mission to make research more accessible. 'By expanding access to research and delivering trustworthy data, we can empower individual wellness journeys—and when we do, everyone benefits,' said .

这项研究通过 People Science 创新的数字临床试验平台 Chloe 进行，体现了使研究更易获取的更广泛使命。 “通过扩大研究的可及性并提供可靠的数据，我们可以助力个人健康之旅——当我们这样做时，每个人都会受益，”

Belinda Tan

贝琳达·谭

, Co-CEO and Co-founder of People Science.

，People Science的联合首席执行官和联合创始人。

'This trial is a major step forward in understanding how GABA-producing probiotics can influence mood and mental well-being through the gut-brain axis,'

“这项试验是在理解通过肠脑轴GABA生产益生菌如何影响情绪和心理健康方面迈出的重要一步，”

said

说

Todd Beckman

托德·贝克曼

, CEO of Verb Biotics.

Verb Biotics公司首席执行官。

'Partnering with People Science allowed us to deliver a high-quality, real-world clinical study and further validate the potential of LP815™ as a safe, effective solution for supporting mental well-being.'

“与People Science合作使我们能够开展一项高质量的真实世界临床研究，并进一步验证LP815™作为一种安全、有效的支持心理健康的解决方案的潜力。”

GABA (gamma-aminobutyric acid) is the brain's primary inhibitory neurotransmitter, playing a critical role in regulating mood and sleep. By delivering functionally focused health solutions like LP815™, Verb Biotics is pioneering a new era of gut-brain health designed to meet the growing consumer demand for natural, science-backed mental wellness support..

GABA（γ-氨基丁酸）是大脑的主要抑制性神经递质，在调节情绪和睡眠方面发挥着关键作用。通过提供功能导向的健康解决方案（如LP815™），Verb Biotics正在开创一个肠脑健康的新时代，旨在满足消费者对天然、科学支持的心理健康需求的增长。

'We've long understood the vital role GABA plays within the central nervous system, but now we're seeing how targeted microbial interventions can drive measurable changes in mental health outcomes

“我们早就了解GABA在中枢神经系统中扮演的重要角色，但现在我们看到有针对性的微生物干预可以推动心理健康结果的可测量变化。

,'

，

added

添加

Noah Zimmerman

诺亚·齐默尔曼

, PhD, Chief Scientific Officer at Verb Biotics

博士，Verb Biotics首席科学官

.

。

'This study is a key demonstration of how gut-brain axis solutions can be thoughtfully designed and clinically proven to improve quality of life.'

“这项研究是一个关键的示范，展示了如何精心设计肠脑轴解决方案并进行临床验证以提高生活质量。”

The findings contribute to a growing body of evidence that gut microbiome interventions—particularly those leveraging the gut-brain axis—can unlock new frontiers in accessible mental wellness solutions. Building on these exciting results, Verb Biotics is preparing to launch a new clinical study focused specifically on how LP815™ may impact sleep quality, further expanding scientific understanding of this strain's benefits for overall mental well-being..

这些发现为越来越多的证据做出了贡献，表明肠道微生物组干预——特别是那些利用肠脑轴的干预——可以开启便捷心理健康解决方案的新领域。基于这些令人兴奋的结果，Verb Biotics正准备启动一项新的临床研究，专门聚焦于LP815™如何影响睡眠质量，进一步扩展对该菌株在整体心理健康益处方面的科学理解。

About Verb Biotics

关于动词生物制品

Verb Biotics is a microbiome innovation company aiming to improve human and companion animal health. Verb's 'biotic' ingredients deliver targeted mechanism of actions for functional health categories, such as gut-brain health. To learn more about Verb's microbiome ingredient solutions, please visit .

Verb Biotics 是一家微生物组创新公司，致力于改善人类和伴侣动物的健康。Verb 的“生物”成分通过靶向作用机制为功能性健康类别（如肠脑健康）提供支持。要了解更多关于 Verb 的微生物组成分解决方案，请访问 。

www.verbbiotics.com

www.verbbiotics.com

.

。

About People Science

关于人文科学

Founded by the pioneers of

由先驱者创立

decentralized

去中心化

clinical trials, People Science is dedicated to transforming clinical research by making it more accessible, efficient, and data-driven. To learn more about People Science's clinical research solutions, please visit

临床试验，People Science 致力于通过使其更易获取、更高效和数据驱动来变革临床研究。要了解更多关于 People Science 的临床研究解决方案，请访问

https://peoplescience.health/

https://peoplescience.health/

SOURCE Verb Biotics

来源动词生物群系

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