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破解早期膀胱癌诊断的密码

Cracking the Code to Earlier Bladder Cancer Diagnosis

安斯泰来 等信源发布 2025-05-15 09:49

可切换为仅中文


Bladder cancer kills when caught late – yet symptom awareness remains dangerously low.

膀胱癌在晚期被发现时是致命的——然而症状的认知仍然低得危险。

1

1

Despite a five-year survival rate of just 40% for those diagnosed at Stage 3,

尽管在第3期确诊的患者的五年生存率仅为40%,

2

2

many people delay seeking help, even when symptoms are present. The scale of this delay – the

许多人即使出现症状也拖延寻求帮助。这种拖延的规模——

'symptom to action gap'

“症状到行动的差距”

– remains unknown.

– 仍然未知。

To change this, Astellas has partnered with the

为此,安斯泰来已与

World Bladder Cancer Patient Coalition (WBCPC)

世界膀胱癌患者联盟 (WBCPC)

and behavioral scientists to uncover what's stopping people from acting sooner. By understanding the cultural, emotional and societal barriers to seeking help, we aim to drive earlier diagnosis and improve outcomes for people affected by this overlooked disease around the world.

和行为科学家揭露阻止人们尽快采取行动的原因。通过了解寻求帮助的文化、情感和社会障碍,我们旨在推动更早的诊断,改善世界各地受这一被忽视疾病影响的人们的治疗效果。

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Understanding the scale of the challenge

理解挑战的规模

Existing understanding and research focuses on patient experience of diagnosis and treatment. We know far less however, about what factors influence how quickly people seek medical support for their symptoms.

现有的理解和研究侧重于患者对诊断和治疗的体验。然而,我们对哪些因素影响人们寻求症状医疗支持的速度知之甚少。

Learning more about the experience from symptom identification to diagnosis could help us to identify triggers to support earlier diagnoses and better outcomes. In collaboration with a team of behavioral scientists, four areas of research have been identified to explore further and unlock potential solutions:.

进一步了解从症状识别到诊断的整个过程,可以帮助我们找出触发因素,从而支持更早期的诊断和更好的结果。在与行为科学家团队的合作下,已经确定了四个研究领域,以进一步探索并挖掘潜在的解决方案:

Symptom attribution and normalization

症状归因与正常化

– when urinary symptoms are normalized or mistaken for other causes (e.g., stress, pre-existing condition, a urinary infection, menstrual period aging)

- 当泌尿系统症状正常化或被误认为是其他原因(例如,压力、先前存在的疾病、尿路感染、月经期老化)时

Psychological factors

心理因素

– the influence of emotional and psychological factors, including fear, embarrassment, denial, which may discourage care-seeking behavior

情感和心理因素的影响,包括恐惧、尴尬、否认,这些可能阻碍寻求护理的行为。

Societal attitudes, gender and cultural norms

社会态度、性别和文化规范

– people’s expectations of care and trust in healthcare systems and comfort levels in seeking care

人们对医疗系统的关怀期望、信任程度以及寻求医疗服务时的舒适度

Health literacy

健康素养

– people’s confidence in understanding symptoms, discussing health issues and the care options available

- 人们对症状的理解、健康问题的讨论以及可用护理选项的信心

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What next?

接下来是什么?

Astellas has partnered with the World Bladder Cancer Patient Coalition (WBCPC) and a team of behavioral scientists to crack the code to earlier diagnosis. We’re driving behavioral science-powered research to uncover what drives or delays action – and to find new ways to help people get the care they need, faster..

安斯泰来与世界膀胱癌患者联盟 (WBCPC) 和行为科学家团队合作,破解早期诊断的密码。我们正在推动行为科学驱动的研究,以揭示是什么促使或延迟了行动,并找到帮助人们更快获得所需护理的新方法。

Our first-of-its-kind research in the US, France, Italy and Germany aims to close the critical gap between recognizing potential bladder cancer symptoms and seeking earlier diagnoses and care. Our aim is to generate insights that will help us better engage with and encourage at-risk members of the general public to take action early..

我们率先在美国、法国、意大利和德国开展了研究,旨在弥合识别潜在膀胱癌症状与寻求早期诊断和治疗之间的关键差距。我们的目标是生成有助于我们更好地与高风险公众互动并鼓励他们及早采取行动的见解。

REFERENCES:

参考文献:

1. Zhang Y, Rumgay H, Li M, Yu H, Pan H, Ni J. The global landscape of bladder cancer incidence and mortality in 2020 and projections to 2040. J Glob Health. 2023 Sep 15;13:04109. Available at:

1. 张 Y,兰佩 H,李 M,余 H,潘 H,倪 J。2020年全球膀胱癌发病率和死亡率的现状及到2040年的预测。《全球健康杂志》。2023年9月15日;13:04109。可访问于:

https://pmc.ncbi.nlm.nih.gov/articles/PMC10502766/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10502766/

. Accessed May 2025.

. 2025年5月访问。

2. Cancer Research UK. Survival for bladder cancer. Available at:

2. 英国癌症研究中心。膀胱癌的生存率。可访问:

https://www.cancerresearchuk.org/about-cancer/bladder-cancer/survival

https://www.cancerresearchuk.org/about-cancer/bladder-cancer/survival

. Accessed May 2025.

. 2025年5月访问。

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