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Led by Khosla Ventures, the financing follows the release of Circulate's trial study, the first of its kind to demonstrate the effectiveness of TPE in improving healthspan and reducing biological age
由Khosla Ventures领投,此次融资是在Circulate发布其试验研究之后进行的,这是首个证明TPE在延长健康寿命和减少生物年龄方面有效性的研究。
NOVATO, Calif.
诺瓦托,加利福尼亚州
,
,
July 2, 2025
2025年7月2日
/PRNewswire/ --
/美通社/ --
Circulate Health
健康循环
, a longevity startup dedicated to harnessing the potential of therapeutic plasma exchange (TPE) to advance human healthspan and lifespan, announced today that it raised
,一家致力于利用治疗性血浆置换(TPE)潜力来延长人类健康寿命和寿命的长寿初创公司,今天宣布筹集了
$12 million
1200万美元
in a seed funding led by Khosla Ventures, with participation from Seaside Ventures and CSC Ventures.
由Khosla Ventures领投,Seaside Ventures和CSC Ventures参投的种子轮融资。
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A patented method of therapeutic plasma exchange uses a procedure that separates, removes, and replaces a patient's plasma to treat inflammation, improve healthspan, and address certain chronic diseases. Circulate has been operating in stealth for the past three years, studying the benefits of TPE and its ability to improve human healthspan and address the hallmarks of again, while partnering with clinics to deliver TPE across the country and soon internationally..
一种获得专利的治疗性血浆置换方法采用了一种分离、去除并替换患者血浆的程序,用于治疗炎症、改善健康寿命以及应对某些慢性疾病。Circulate 在过去三年里一直秘密运营,研究 TPE 的益处及其改善人类健康寿命和应对衰老标志的能力,同时与诊所合作,在全国范围内提供 TPE 服务,并即将拓展至国际。
'Khosla's investment in our work demonstrates the power of what we're doing,' said Brad Younggren MD, CEO & co-founder.
“科斯拉对我们工作的投资证明了我们所做事情的力量,”布拉德·杨格伦医学博士、首席执行官兼联合创始人表示。
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Circulate was founded based on scientific research from world-renowned geroscientist
Circulate 是基于世界知名的老年科学家的科学研究创立的。
Eric Verdin
埃里克·维尔丁
, MD, who is a co-founder of Circulate and CEO of the Buck Institute of Research on Aging. In partnership with the Buck Institute and led by scientific advisor David Furman PhD, Circulate recently
,医学博士,Circulate的联合创始人兼巴克老龄化研究所的首席执行官。Circulate最近在与巴克研究所的合作下,并由科学顾问大卫·菲尔曼博士领导,
published a clinical trial
发表了临床试验
that found TPE combined with intravenous immunoglobin (IVIG) reduced patients' biological age by an average of 2.6 years, as measured by multi-omics biomarkers.
发现TPE联合静脉注射免疫球蛋白(IVIG)可使患者的生物学年龄平均减少2.6年,这是通过多组学生物标志物测量得出的结果。
'We have been immensely dedicated to our research and delivering the highest quality medical care to patients and clinic partners in order to further address healthspan, and the hallmarks of aging,' said
“我们一直全力以赴地投入研究,并为患者和诊所合作伙伴提供最高质量的医疗服务,以进一步解决健康寿命和衰老的标志性问题,”
Brad Younggren
布拉德·杨格伦
, MD, CEO and co-founder of Circulate. 'Khosla Ventures' investment into our work truly demonstrates the power of and potential for the work we're doing. We plan to use these additional funds to expand our clinic network across the country and internationally, and provide greater access to those seeking access to a therapy shown to improve biomarkers and biological clocks.'.
医学博士,Circulate的首席执行官兼联合创始人表示:“Khosla Ventures对我们工作的投资真正展示了我们所做工作的力量和潜力。我们计划利用这些额外的资金,在全国和国际上扩展我们的诊所网络,并为那些寻求获得一种被证明可以改善生物标志物和生物钟的疗法的人提供更大的访问机会。”
'We incubated Circulate to explore whether a safe, well-understood therapy like TPE could counter the deleterious effects of aging, and offer broader health benefits like potentially removing microplastics from the body,' said
“我们孵化了Circulate,以探索一种安全且易于理解的疗法(如TPE)是否能够对抗衰老的有害影响,并提供更广泛的健康益处,比如可能清除体内的微塑料,”
Alex Morgan
亚历克斯·摩根
of Khosla Ventures. 'Early clinical results are promising, and we're excited to continue backing the team as they work to make TPE more accessible to more people.'
科斯拉创投的。“早期临床结果很有希望,我们很高兴继续支持该团队,因为他们致力于让更多人更容易获得TPE。”
Circulate scientific advisory board also includes Matt Kaeberlein PhD and
科学顾问委员会成员还包括马特·凯伯莱博士和
Alex Aravanis
亚历克斯·阿拉瓦尼斯
MD PhD, both providing additional expertise and strategic guidance.
医学博士,两者均提供额外的专业知识和战略指导。
Circulate Health already has 24 partner clinics, across 8 states, and the Circulate Network is expected to grow to over 50 clinics by the end of 2025 in the U.S. and abroad.
Circulate Health已经在8个州拥有24家合作诊所,预计到2025年底,Circulate网络将扩展至美国及海外超过50家诊所。
Clinicians and patients can learn more about Circulate at
临床医生和患者可以访问以下网址了解有关Circulate的更多信息
www.circulate.health
www.circulate.health
.
。
About Circulate Health
关于Circulate Health
Circulate Health is pioneering technologies to improve healthspan and reduce biological age.
Circulate Health 正在开创技术以延长健康寿命并减少生物年龄。
SOURCE Circulate Health
来源:Circulate Health
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