by Mark Chiang

由马克·蒋

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Compass Pathways has released results from a late-stage clinical trial evaluating its psilocybin-based therapy for treatment-resistant depression. While the findings indicate some positive outcomes, they have sparked questions about the overall effectiveness of the therapy and its potential utility as a treatment option.

Compass Pathways发布了其基于裸盖菇素的治疗难治性抑郁症的晚期临床试验结果。尽管研究结果表明有一些积极的效果，但也引发了人们对该疗法整体有效性及其作为治疗选择的潜在用途的质疑。

The data, which were part of a Phase 3 study, did not appear to significantly bolster investor confidence in the company’s approach..

这些数据是第三阶段研究的一部分，似乎并没有显著增强投资者对公司方法的信心。

The trial focused on Compass’ proprietary formulation of psilocybin, a psychedelic compound being studied for its therapeutic effects in mental health conditions. The results showed some level of efficacy in addressing symptoms of depression among participants who had not responded to other treatments.

这项试验聚焦于Compass的裸盖菇素专利配方，这是一种正在研究其在心理健康疾病中治疗效果的精神活性化合物。结果显示，在对其他治疗无反应的参与者中，该药物在缓解抑郁症状方面显示出一定程度的疗效。

However, analysts and stakeholders have raised concerns about how impactful these findings are in positioning psilocybin as a viable mainstream treatment for depression. Following the release of the data, market reactions suggested skepticism regarding the commercial and clinical prospects of Compass’ product..

然而，分析师和利益相关者对这些发现对于将裸盖菇素定位为治疗抑郁症的主流可行疗法有多大影响表示担忧。数据发布后，市场的反应表明人们对Compass产品的商业和临床前景持怀疑态度。

Further details on the trial’s methodology or specific metrics were not disclosed in this report.

该报告未披露有关试验方法或具体指标的更多细节。

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Source: GO-AI-ne1

来源：GO-AI-ne1

Date: June 23, 2025

日期：2025年6月23日

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Mark Chiang

蒋志光

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