Spear Bio推出下一代超灵敏免疫分析解决方案SPEAR UltraDetect™，以变革神经退行性疾病研究-动脉网

Spear Bio Launches Next Generation Ultrasensitive Immunoassay Solution SPEAR UltraDetect™ to Transform Neurodegenerative Disease Research

CISION 等信源发布 2025-07-25 21:07

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WOBURN, Mass.

马萨诸塞州伍伯恩

，

July 25, 2025

2025年7月25日

/PRNewswire/ -- Spear Bio, a biotechnology company pioneering homogeneous ultrasensitive immunoassay technology, today announced the commercial launch of its SPEAR UltraDetect™ immunoassay solution. It delivers unparalleled sensitivity, specificity, precision, and scalability for robust biomarker measurement.

/PRNewswire/ -- Spear Bio是一家开创均相超灵敏免疫测定技术的生物技术公司，今天宣布其SPEAR UltraDetect™免疫测定解决方案的商业发布。该解决方案为强大的生物标志物测量提供了无与伦比的灵敏度、特异性、精确性和可扩展性。

The initial launch includes four assays, targeting key neurology biomarkers: phosphorylated tau 231 (pTau231), phosphorylated tau 217 (pTau217), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL). Spear Bio will collaborate with .

最初的发布包括四种检测方法，针对关键的神经生物标志物：磷酸化tau 231（pTau231）、磷酸化tau 217（pTau217）、胶质纤维酸性蛋白（GFAP）和神经丝轻链（NfL）。Spear Bio将与之合作。

Bio-Techne

生物科技

to distribute SPEAR UltraDetect immunoassays globally.

在全球范围内分发SPEAR UltraDetect免疫分析。

Unlike traditional ultrasensitive technologies, which rely on heterogeneous formats that require solid surface capture and multiple wash steps, Spear Bio's proprietary SPEAR technology is the first homogeneous immunoassay platform that achieves ultra-sensitivity without wash steps. It precisely quantifies protein biomarkers at attomolar concentrations from as little as 1 µl of diluted sample, greatly surpassing the most sensitive heterogeneous platforms on the market..

不同于依赖异质格式、需要固体表面捕获和多次清洗步骤的传统超灵敏技术，Spear Bio的专有SPEAR技术是首个无需清洗步骤即可实现超高灵敏度的均质免疫测定平台。它能够从低至1微升的稀释样本中精确量化阿摩尔浓度的蛋白质生物标志物，远远超越市场上最敏感的异质平台。

SPEAR technology further addresses longstanding specificity challenges by eliminating the non-specific binding common in heterogeneous assays, significantly reducing false-positive results. Its innovative two-factor authentication mechanism ensures that signal arises only when antibody pairs are co-localized on target proteins over an extended period of time..

SPEAR技术通过消除在异质测定中常见的非特异性结合，进一步解决了长期存在的特异性挑战，显著减少了假阳性结果。其创新的双重认证机制确保只有当抗体对在目标蛋白上共定位超过一段时间时，信号才会产生。

The unparalleled sensitivity, specificity and precision provided by SPEAR UltraDetect immunoassays are key for reliably measuring low-abundance neurology biomarkers, especially in peripheral blood where these are often present at trace levels due to the blood-brain barrier. SPEAR UltraDetect immunoassays can be read on a wide range of qPCR systems adopted in research and clinical labs, with highly consistent results across different qPCR instruments and formats.

SPEAR UltraDetect 免疫测定提供的无与伦比的灵敏度、特异性和精确性是可靠测量低丰度神经生物标志物的关键，尤其是在外周血中，由于血脑屏障的存在，这些标志物通常以痕量水平存在。SPEAR UltraDetect 免疫测定可以在研究和临床实验室中广泛采用的各种qPCR系统上读取，并且在不同qPCR仪器和格式之间结果高度一致。

This enables unique robustness, scalability, and ease of integration into existing laboratory workflows..

这使得其具有独特的稳健性、可扩展性，并且易于整合到现有的实验室工作流程中。

'We are proud to deliver the first of its kind ultrasensitive immunoassay solution that could potentially solve the challenges that neurology researchers working with blood-based biomarkers have faced for years,' said

“我们很自豪能够提供一种前所未有的超灵敏免疫分析解决方案，这可能会解决多年来从事基于血液的生物标志物研究的神经学研究人员面临的挑战。”

Feng Xuan

冯谖

, PhD, Co-founder and CEO of Spear Bio. 'SPEAR UltraDetect will empower academic and clinical researchers worldwide to unlock new insights and improve therapies and treatments for a variety of neurological conditions.'

博士，Spear Bio的联合创始人兼首席执行官。'SPEAR UltraDetect将使全球的学术和临床研究人员能够解锁新的见解，并改善各种神经系统疾病的治疗和治疗方法。'

The SPEAR UltraDetect immunoassay solution will be showcased at the 2025 Alzheimer's Association International Conference (AAIC), July 27–30 in

SPEAR UltraDetect 免疫分析解决方案将在2025年7月27日至30日举行的阿尔茨海默病协会国际会议（AAIC）上展示。

Toronto, Canada

加拿大多伦多

, Booth #1527.

，展位号1527。

About Spear Bio

关于Spear Bio

Founded in 2021 and headquartered in

成立于2021年，总部位于

Woburn, Massachusetts

马萨诸塞州沃本

, Spear Bio is dedicated to its mission of revolutionizing biomarker research and diagnostics through innovation and accessibility. Leveraging its unique homogeneous assay format, SPEAR technology consistently delivers highly sensitive and precise protein measurements. Spear Bio envisions a future where high-performance assays democratize access to critical insights, accelerating progress in research and medicine worldwide.

Spear Bio致力于通过创新和可及性彻底改变生物标志物研究和诊断的使命。利用其独特的均相检测形式，SPEAR技术始终提供高度灵敏且精确的蛋白质测量。Spear Bio设想了一个未来，高性能检测将使关键见解的获取民主化，加速全球研究和医学的进步。

。

Learn more about Spear Bio

了解有关Spear Bio的更多信息

。

Media Contact:

媒体联系人：

info@spear.bio

SOURCE Spear Bio

来源：Spear Bio

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