A key vaccine committee hand-picked by Robert F. Kennedy Jr. closely scrutinized the childhood immunization schedule at a high-stakes meeting Friday, in the latest indication the panel may consider additional changes in the future.

由小罗伯特·F·肯尼迪亲自挑选的一个关键疫苗委员会在周五的一次高风险会议上仔细审查了儿童免疫接种计划，这进一步表明该小组未来可能会考虑进行更多调整。

The committee, which voted earlier in the day to change a decades-old standard for hepatitis B vaccines, didn’t vote on any new recommendations for the routine practices that inoculate children against a bevy of other infectious diseases. But in an hours-long discussion, they focused on whether that schedule may increase the risk of chronic conditions despite extensive research proving otherwise..

该委员会当天早些时候投票决定改变已使用数十年的乙型肝炎疫苗标准，但并未对为儿童接种预防一系列其他传染病的常规做法提出任何新建议。但在长达数小时的讨论中，他们重点关注的是，尽管有大量研究证明并非如此，但该时间表是否可能增加患慢性病的风险。

The

The

immunization schedule

免疫接种时间表

calls for vaccines to be administered at certain milestones in a child’s life

要求在儿童成长的特定阶段接种疫苗

. The series includes inoculations against many diseases that can lead to severe illness, such as polio, measles and

该系列包括针对许多可能导致严重疾病的疫苗接种，例如脊髓灰质炎、麻疹和

tetanus, among others. It’s been demonstrated as generally safe and effective through decades of research, and has been credited with

破伤风等。通过数十年的研究，它已被证明通常是安全和有效的，并且被赞誉为

saving millions of lives

挽救数百万人的生命

across the world.

世界各地。

“We've had at least two children die from the measles in the United States in the last year. It's 100% preventable. I think the safety of vaccines is something that has been demonstrated over and over and over again, decades of use in billions of babies around the world,” said

“在过去的一年中，美国至少有两名儿童死于麻疹。这是100%可以预防的。我认为疫苗的安全性已经通过全世界数十亿婴儿数十年的使用一次又一次地得到了证明。”

Kawsar Talaat, an infectious disease physician and associate professor in the Department of International Health at the Johns Hopkins Bloomberg School of Public Health, in an interview with BioPharma Dive.

塔拉特·卡瓦萨，约翰霍普金斯大学布隆伯格公共卫生学院国际卫生系传染病医生和副教授，在接受《生物制药潜水》采访时。

Yet the immunization schedule has long been a target of Kennedy, the Secretary of Health and Human Services and a prominent anti-vaccine activist. As the head of HHS, he’s reformed the vaccine advisory panel, ACIP, and stacked it with multiple members aligned with his views. That panel has already questioned the safety and impact of multiple shots and now softened support for the hepatitis B vaccine.

然而，免疫接种计划长期以来一直是卫生与公众服务部部长、著名的反疫苗活动人士肯尼迪的目标。作为卫生与公众服务部的负责人，他改革了疫苗咨询小组ACIP，并在其中安插了多位与其观点一致的成员。该小组已经对多种疫苗的安全性与影响提出质疑，并且现在对乙型肝炎疫苗的支持也有所减弱。

It’s also increasingly hearing presentations from sources with a history of vaccine skepticism..

它还越来越多地听到那些有疫苗怀疑历史的来源所做的报告。

Friday’s presenters were the latest example. One was Aaron Siri, a lawyer who’s sued vaccine manufacturers and petitioned the FDA to revoke the polio vaccine. The other was Tracy Beth H

周五的演讲者是最新例子。其中之一是艾伦·西里，他是一名律师，曾起诉过疫苗制造商并要求食品药品监督管理局撤销小儿麻痹症疫苗。另一位是 Tracy Beth H

ø

ø

eg, a COVID vaccine critic recently named to one of the agency’s highest-ranking positions.

例如，一位最近被任命为该机构最高职位之一的新冠疫苗批评者。

In a

在

76-page slide deck

76页幻灯片

, Siri falsely claimed that most childrens’ vaccines were not tested against a control or a placebo prior to approval.

，Siri错误地声称大多数儿童疫苗在批准之前并未与对照组或安慰剂进行测试。

Many were

许多人都

, according to the American Academy of Pediatrics. Siri additionally argued against the cumulative number of shots kids receive and the way they’re spaced out compared to other countries, echoing a talking point from anti-vaccine groups — which scientists have

，根据美国儿科学会的说法。Siri还反对孩子们接受的累积注射数量以及它们与其他国家相比的间隔方式，这呼应了反疫苗团体的 talking point —— 科学家们对此已

refuted

驳斥

— that these inoculations overwhelm the immune system.

这些疫苗接种会压垮免疫系统。

He also contended more safety data is needed, and that all of ACIP’s vaccine recommendations should involve “shared decision making,” a weaker endorsement in which a clinician and patient work together to make a medical decision.

他还表示，需要更多的安全数据，并且 ACIP 的所有疫苗建议都应涉及“共同决策”，这是一种较弱的认可，即临床医生和患者共同努力做出医疗决定。

Cody Meissner, an expert in pediatric infectious disease epidemiology, vaccine development and immunization safety, castigated Siri afterwards, calling his work a “terrible distortion of all the facts.” The spike in vaccines administered has resulted in plummeting rates of infectious disease in the U.S., he noted, and an adverse event that occurs around the time of vaccination doesn’t prove the shot was to blame..

科迪·迈斯纳是儿科传染病流行病学、疫苗开发和免疫安全性方面的专家，他随后谴责了西里，称他的工作是“对所有事实的严重歪曲”。他指出，美国疫苗接种数量的激增导致了传染病发病率的骤降，而接种疫苗前后发生的不良事件并不能证明是疫苗导致的。

“All you're focusing on are these very rare, ill-defined side effects, and completely ignoring the extraordinary benefit and promise that these vaccines apply to us,” Meissner said, contending Siri shouldn’t have been invited to speak in the first place.

“你所关注的只是这些非常罕见、定义不清的副作用，而完全忽视了这些疫苗给我们带来的非凡益处和希望，”梅斯纳说，他认为西里根本不应该被邀请发言。

H

H

ø

ø

eg

例如

, meanwhile

，同时

, compared the U.S. and Danish vaccination schedules, highlighting how Denmark requires fewer immunizations for children. She also claimed

，比较了美国和丹麦的疫苗接种计划，强调丹麦对儿童的免疫要求较少。她还声称

there to be an association between vaccination and chronic health issues, noting how the rates of such health problems have climbed 'precipitously' since the early 1980s.

认为疫苗接种与慢性健康问题之间存在关联，指出自20世纪80年代初以来，此类健康问题的发生率“急剧”攀升。

No evidence was presented linking vaccines to a rise in chronic diseases. And Adam Langer, the

没有证据表明疫苗与慢性病的增加有关。而且亚当·兰格，

CDC’s acting director for the National Center for HIV, Viral Hepatitis, STD, and TB Prevention, noted Denmark’s smaller population and different healthcare system make it a misleading comparator to the U.S.

美国疾病控制与预防中心（CDC）国家艾滋病毒、病毒性肝炎、性病和结核病预防中心的代理主任指出，丹麦人口较少且医疗系统不同，这使其成为与美国比较时会产生误导的参照对象。

“So let's talk about apples to apples, not apples to oranges,” Langer said.

“所以让我们谈谈苹果对苹果，而不是苹果对橙子，”兰格说。

Multiple ACIP members also focused on the use of aluminum in immunizations. Aluminum has been safely used for decades as an immune-boosting adjuvant in more than a dozen standard childhood vaccinations. A

多个ACIP成员还关注了铝在免疫接种中的使用。几十年来，铝一直被安全地用作十几种标准儿童疫苗中的增强免疫的佐剂。

massive study

大规模研究

evaluating the impact of aluminum adjuvants in over 1 million children in Denmark over the course of three decades

评估丹麦超过100万名儿童在三十年内铝佐剂的影响

found no link between

没有发现...之间的联系

exposure and a wide range of chronic conditions.

暴露和广泛的慢性疾病。

And Talaat noted how the aluminum exposures from diets and the surrounding environment are “so much more” than what’s contained in vaccines.

塔拉特指出，饮食和周围环境中摄入的铝“远远多于”疫苗中所含的量。

ACIP panelists didn’t say they intended to recommend the elimination of aluminum salts from vaccines, more that they wanted to elevate a discussion about the potential risks and have a work group examine it in the future.

ACIP专家小组成员并没有表示他们打算建议从疫苗中去除铝盐，而是更希望提升对潜在风险的讨论，并在未来让一个工作组对其进行研究。

Removal, though, would usher in major challenges for vaccine manufacturers. New vaccine formulations would take years to develop and test and potentially affect the availability

不过，移除（专利保护）将给疫苗制造商带来重大挑战。新疫苗配方需要数年时间来开发和测试，并可能影响可用性。

of several shots, including inoculations against HPV, meningococcal B and hepatitis A and B, among others.

包括针对HPV、B型脑膜炎球菌和甲型和乙型肝炎等的多针疫苗。