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Researchers have identified key cellular components within the tumor microenvironment of metastatic bladder cancer, shedding light on factors that contribute to disease progression. A study published in the *Journal of Translational Medicine* highlights the role of myofibroblasts as prognostic indicators in metastatic bladder cancer.
研究人员已经确定了转移性膀胱癌肿瘤微环境中的关键细胞成分,揭示了导致疾病进展的因素。发表在《转化医学杂志》上的一项研究强调了肌成纤维细胞作为转移性膀胱癌预后指标的作用。
The research team, led by Z. Wang, J. Miao, and M. Wang, examined how specific cellular compositions influence metastasis and provide critical insights into the mechanisms driving cancer spread..
研究团队由王Z.、苗J.和王M.领导,研究了特定细胞组成如何影响转移,并提供了对驱动癌症扩散机制的关键见解。
The study focused on analyzing the tumor microenvironment to better understand its impact on bladder cancer progression. Researchers found that myofibroblasts play a significant role in shaping this environment and may serve as predictive markers for disease outcomes. By mapping these cellular interactions, the findings offer a deeper understanding of how tumors evolve and metastasize.
该研究聚焦于分析肿瘤微环境,以更好地理解其对膀胱癌进展的影响。研究人员发现肌成纤维细胞在塑造这一环境中发挥了重要作用,并可能作为疾病预后的预测标志物。通过绘制这些细胞相互作用的图谱,研究结果为肿瘤如何演变和转移提供了更深入的认识。
This research adds to existing knowledge about bladder cancer biology and opens avenues for further exploration into targeted therapies or diagnostic tools based on tumor microenvironment dynamics..
这项研究增加了对膀胱癌生物学的现有知识,并为进一步探索基于肿瘤微环境动态的靶向疗法或诊断工具开辟了途径。
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Date: December 15, 2025
日期:2025年12月15日
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