Manifold Raises $18 Million Series B to Define Vertical AI for Life Sciences and Accelerate Life-changing Medicines to Patients

Manifold筹集了1800万美元的B轮融资，用于定义生命科学领域的垂直人工智能，并加速将改变生命的药物带给患者。

The new funding cements Manifold’s leadership in the $2 trillion life sciences market, powering next-generation AI workflows from early discovery through precision care.

新的资金巩固了Manifold在2万亿美元生命科学市场中的领导地位，推动从早期发现到精准护理的下一代AI工作流程。

NEWTON, Mass., December 18, 2025-- Manifold, the AI platform for life sciences, today announced an $18 million Series B funding round led by Reach Capital, with participation from SilverArc Capital, Industry Ventures, and existing investors TQ Ventures and Calibrate Ventures. The round brings Manifold’s total capital raised to $40 million and positions the company as the emerging category leader in vertical AI for life sciences.

马萨诸塞州牛顿市，2025年12月18日——生命科学领域的人工智能平台Manifold今日宣布完成了一轮由Reach Capital领投的1800万美元B轮融资，SilverArc Capital、Industry Ventures以及现有投资者TQ Ventures和Calibrate Ventures参与了本轮融资。此轮融资使Manifold筹集的总资本达到4000万美元，并确立了该公司作为生命科学垂直领域人工智能新兴领导者的地位。

Manifold’s platform is transforming how biopharma companies and medical centers accelerate workflows from target identification to clinical development, market access, and precision medicine in the clinic..

Manifold的平台正在改变生物制药公司和医疗中心如何加速从靶点识别到临床开发、市场准入以及临床精准医疗的工作流程。

Defining Vertical AI for Life Sciences

定义生命科学领域的垂直人工智能

Vertical AI platforms are transforming productivity in major industries—legal services, financial services, customer experience, and more—with support for domain-specific data, workflows, and governance that go much deeper than horizontal platforms.

垂直人工智能平台正在通过支持特定领域的数据、工作流程和治理，深刻变革法律服务、金融服务、客户体验等主要行业的生产力，其深度远超横向平台。

In life sciences, a $2 trillion industry where productivity directly impacts patient outcomes, Manifold is defining this category. This field requires purpose-built infrastructure for multi-entity collaboration, multimodal biomedical data, and workflows that span from bench to clinic. Manifold's platform is purpose-built for this complexity..

在生命科学领域，这是一个价值2万亿美元的产业，生产力直接影响患者结果，Manifold正在定义这一类别。该领域需要为多实体协作、多模态生物医学数据以及从实验室到诊所的工作流程专门构建的基础设施。Manifold的平台正是为应对这种复杂性而量身打造的。

“In every industry, companies that combine agentic AI and domain-specific context will transform productivity. Customers are seeking proven partners in this transformation. We believe Manifold is the emerging category leader for vertical AI in life sciences,” said Jennifer Carolan, Partner at Reach Capital..

“在每个行业中，结合代理型人工智能和领域特定背景的公司将改变生产力。客户正在寻找这一转型中经过验证的合作伙伴。我们相信 Manifold 是生命科学领域垂直人工智能新兴的类别领导者，”Reach Capital 的合伙人詹妮弗·卡罗兰 (Jennifer Carolan) 表示。

Accelerating Agent Development and the Data Flywheel

加速代理开发和数据飞轮

The new funding will enable Manifold to advance its platform with capabilities that materially improve life sciences productivity:

新的资金将使Manifold能够通过显著提升生命科学生产力的功能来推进其平台：

• Expand the Agent OS: Advancing how AI agents operate on multimodal biomedical data, use scientific tools, and leverage institutional context to accelerate work, from biomarker development and model validation through trial design and real-world evidence generation.

• 扩展Agent OS：推进AI代理在多模态生物医学数据上的操作方式，使用科学工具，并利用机构背景来加速工作，从生物标志物开发和模型验证到试验设计和真实世界证据生成。

• Deepen collaboration infrastructure: Extending features that enable teams to share analyses, reuse context, and work across organizational boundaries with appropriate governance and data sovereignty.

• 深化协作基础设施：扩展功能，使团队能够共享分析、重用上下文，并在适当的治理和数据主权下跨组织边界工作。

• Scale the data ecosystem: Constructing novel datasets becomes easier as more organizations join, compounding value for all participants while maintaining data ownership and governance.

• 扩展数据生态系统：随着更多组织的加入，构建新颖的数据集变得更加容易，为所有参与者带来复合价值，同时保持数据所有权和治理。

Strategic Milestones and Growing Momentum

战略里程碑与不断增长的势头

Over the past year, Manifold has achieved significant milestones that demonstrate both strong product-market fit and compounding network effects:

在过去的一年中，Manifold 达成了多个重要的里程碑，这些成就不仅展示了强劲的产品市场契合度，还体现了不断累积的网络效应：

• Workflow breadth: AI agents which can be tailored to specific datasets and tools across dozens of workflows—from cohort identification and biomarker discovery to treatment pathway analysis and outcomes research.

• 工作流广度：AI代理可以针对数十种工作流中的特定数据集和工具进行定制——从队列识别和生物标志物发现到治疗路径分析和结果研究。

• Enterprise momentum: A growing customer base including leading companies like Foundation Medicine and academic centers like the University of Virginia.

• 企业动力：不断增长的客户群体，包括Foundation Medicine等领先公司以及弗吉尼亚大学等学术中心。

• Strategic collaborations: Deepening strategic collaborations with the Broad Institute, AWS, and Anthropic which strengthen both scientific and technical capabilities and go-to-market reach.

• 战略合作：深化与博德研究所、AWS和Anthropic的战略合作，这不仅增强了科学和技术能力，还扩大了市场推广的覆盖范围。

• Terra operation: As an operator of Terra, Manifold now serves thousands of researchers across hundreds of life sciences organizations globally.

• Terra运营：作为Terra的运营商，Manifold现在为全球数百家生命科学组织的数千名研究人员提供服务。

'Our customers and partners are pushing the boundaries of what's possible in life sciences, and we're honored to build alongside them. This funding accelerates our shared goal to transform productivity in life sciences and get life-changing medicines to patients faster,” said Vinay Seth Mohta, CEO, Manifold..

“我们的客户和合作伙伴正在推动生命科学领域可能性的边界，我们很荣幸能与他们携手共建。这笔资金将加速我们共同的目标，即变革生命科学领域的生产力，更快地将改变生命的药物带给患者。” Manifold首席执行官Vinay Seth Mohta表示。

For an inside look at the vision driving Manifold’s next phase of growth, visit the CEO blog.

要深入了解推动Manifold下一阶段增长的愿景，请访问首席执行官博客。

About Manifold

关于流形

Manifold is the AI platform for life sciences, accelerating life-changing medicines to patients. Our products speed up workflows in areas from target identification and clinical development to market access and precision medicine in the clinic, while maintaining the governance life sciences requires.

Manifold是生命科学领域的人工智能平台，加速将改变生命的药物带给患者。我们的产品在从靶点识别、临床开发到市场准入及临床精准医疗等领域加快工作流程，同时满足生命科学所需的监管要求。

Global companies and premier research institutions use Manifold to operate faster and more effectively. Backed by leading investors including Reach Capital, TQ Ventures, Calibrate Ventures, SilverArc Capital, and Industry Ventures, Manifold serves tens of thousands of users across hundreds of organizations globally..

全球公司和一流研究机构使用Manifold来更快、更有效地运作。在Reach Capital、TQ Ventures、Calibrate Ventures、SilverArc Capital和Industry Ventures等领先投资者的支持下，Manifold为全球数百个组织中的数万名用户提供服务。

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Alec Biedrzycki

亚历克·比德辛斯基

VP of Marketing

市场营销副总裁

Manifold AI

流形AI

press@manifold.ai

press@manifold.ai