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修丽可®宣布两项经同行评审的临床研究证明了THD抗坏血酸在C+修正复合物30%®中的美容功效

Revision Skincare® Announces Two Peer‑Reviewed Clinical Studies Demonstrating the Cosmetic Benefits of THD Ascorbate in C+ Correcting Complex 30%®

PR Newswire 等信源发布 2026-04-10 01:41

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IRVING, Texas

欧文,德克萨斯州

,

Apr. 9, 2026

2026年4月9日

/PRNewswire/ -- Revision Skincare®, a physician‑dispensed medical‑grade skincare company focused on clinically validated innovation, today announced the publication of two peer‑reviewed clinical studies in the

/PRNewswire/ -- Revision Skincare®,一家专注于临床验证创新的医生配发的医疗级护肤公司,今天宣布在

Journal of Cosmetic Dermatology

化妆品皮肤病学杂志

. The studies evaluate the cosmetic efficacy, tolerability and visible skin benefits of **

这些研究评估了**的美容功效、耐受性和可见的皮肤益处。

C+ Correcting Complex 30%

C+ 修正复合物 30%

®

®

, a high‑strength vitamin C formulation featuring tetrahexyldecyl ascorbate (THD ascorbate).

,一种含有四己基癸基抗坏血酸(THD抗坏血酸)的高浓度维生素C配方。

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Revision Skincare® C+ Correcting Complex 30%®, a high‑strength vitamin C serum formulated with THD ascorbate, is clinically studied to support brighter‑looking skin, improved tone evenness and visible skin quality.

修丽可® C+ 纠正复合物 30%®,一种高浓度维生素C精华,采用THD抗坏血酸配方,经临床研究证明可提亮肤色、改善肤质均匀度并提升可见的皮肤质量。

In collaboration with Dr. Ryan Kelm, MD, Dr. May Hall, DO, FAAD and Dr. McKenzie Maloney, MD, the studies evaluate THD ascorbate across penetration science, molecular and histologic testing, and randomized, double‑blind clinical research, providing a comprehensive view of its cosmetic performance. The findings add to the growing body of peer‑reviewed evidence supporting THD ascorbate as a stable, skin‑compatible vitamin C derivative used in advanced cosmetic skincare formulations..

与医学博士 Ryan Kelm、整骨医学博士 May Hall(FAAD)及医学博士 McKenzie Maloney 合作,这些研究通过渗透科学、分子和组织学测试以及随机双盲临床研究对THD抗坏血酸进行评估,全面展示了其在化妆品中的性能。研究结果进一步增加了经同行评议的证据支持,证明THD抗坏血酸是一种稳定且与皮肤相容的维生素C衍生物,广泛应用于先进的化妆品护肤配方中。

'At Revision Skincare, clinical validation is foundational to how we prove our products' efficacy,' said Dr. Alisar Zahr, vice president of research and clinical development at Revision Skincare®. 'The publication of these peer‑reviewed studies underscores our commitment to rigorous science and highlights the role of THD ascorbate within C+ Correcting Complex 30%® as part of our evidence‑based approach to skincare innovation.'.

“在Revision Skincare,临床验证是我们证明产品功效的基础,” Revision Skincare®研发和临床开发副总裁Alisar Zahr博士表示。“这些经过同行评审的研究的发表,彰显了我们对严谨科学的承诺,并突出了THD抗坏血酸在C+ Correcting Complex 30%®中的作用,这是我们基于证据的护肤创新方法的一部分。”

What Was Studied?

研究了什么?

The published research focuses on a high‑concentration THD ascorbate formulation and its ability to visibly improve multiple markers of skin quality when used consistently as part of a topical skincare regimen.

发表的研究聚焦于一种高浓度的THD抗坏血酸配方,以及其作为局部护肤程序的一部分持续使用时明显改善皮肤质量多个指标的能力。

THD ascorbate is a lipid‑soluble vitamin C derivative used in cosmetic science for its formulation stability and skin‑mimicking properties. Unlike traditional water‑soluble L‑ascorbic acid, THD ascorbate is designed to better associate with the skin's lipid matrix, supporting penetration into the epidermis and dermis and improved cosmetic bioavailability..

THD抗坏血酸是一种脂溶性维生素C衍生物,因其配方稳定性和仿肤特性而被用于化妆品科学。与传统的水溶性L-抗坏血酸不同,THD抗坏血酸旨在更好地与皮肤的脂质基质结合,支持渗透到表皮和真皮,并提高化妆品的生物利用度。

Key Clinical and Preclinical Findings From the Peer‑Reviewed Studies

同行评审研究中的关键临床和临床前发现

Across both studies, investigators reported:

两项研究的调查人员均报告称:

Visible improvement in overall skin appearance

整体皮肤外观明显改善

Increased skin radiance and brightness

皮肤光泽和亮度增加

Improved tone evenness and surface texture

改善了音调的均匀性和表面纹理

Reduction in the visible appearance of photodamage and uneven pigmentation

减少光损伤和色素不均的可见外观

Demonstrated skin compatibility and cosmetic tolerability during regular use

在常规使用中表现出良好的皮肤相容性和化妆品耐受性

Preclinical findings also demonstrated robust buffering of reactive oxygen species (ROS) induced by high‑energy visible (blue) light, as well as significant inhibition of melanogenesis and improvements in overall skin architecture, including the epidermis, dermal‑epidermal junction and dermis.

临床前研究结果还表明,对高能可见光(蓝光)诱导的活性氧(ROS)具有强大的缓冲作用,同时显著抑制黑色素生成,并改善整体皮肤结构,包括表皮、真皮-表皮交界处和真皮。

Together, these findings support the use of THD ascorbate as an effective vitamin C alternative, delivering visible cosmetic benefits while addressing common formulation, stability and tolerability challenges historically associated with high concentrations of L‑ascorbic acid.

这些发现共同支持将THD抗坏血酸作为有效的维生素C替代品,它在提供显著的美容功效的同时,解决了长期以来与高浓度L-抗坏血酸相关的常见配方、稳定性和耐受性挑战。

Why THD Ascorbate Is a Viable Alternative to L‑Ascorbic Acid and Sodium Ascorbate

为什么THD抗坏血酸是L-抗坏血酸和抗坏血酸钠的可行替代品

L‑ascorbic acid is widely used in cosmetic formulations but can present challenges related to oxidative instability, formulation constraints and skin sensitivity at higher concentrations. Recent vitamin C products have included a salt form of L-ascorbic acid, sodium ascorbate. Both molecules have inherent stability concerns, thus efficacy concerns. .

L-抗坏血酸广泛应用于化妆品配方中,但在较高浓度下可能带来氧化不稳定性、配方限制和皮肤敏感性等挑战。近期的维生素C产品中包含了一种L-抗坏血酸的盐形式——抗坏血酸钠。这两种分子都存在固有的稳定性问题,因此也存在功效上的担忧。

The findings from the published studies demonstrate that high‑concentration THD ascorbate can deliver visible skin benefits comparable to those expected from topical L‑ascorbic acid, while offering advantages in formulation stability, skin compatibility and penetration. These characteristics position THD ascorbate as a practical and clinically relevant option for modern cosmetic skincare formulations, particularly in the evolving landscape of hydroquinone‑free brightening solutions..

已发表的研究结果表明,高浓度THD抗坏血酸可带来与局部使用L-抗坏血酸相当的显著皮肤益处,同时在配方稳定性、皮肤兼容性和渗透性方面具有优势。这些特性使THD抗坏血酸成为现代化妆品护肤配方中实用且临床相关的选项,特别是在不断发展的无氢醌亮肤解决方案领域。

Study Design Overview

研究设计概述

The two peer‑reviewed clinical studies employed structured evaluation methods designed to assess visible skin improvements over time under real‑world cosmetic conditions.

这两项经同行评审的临床研究采用了结构化的评估方法,旨在真实世界的化妆品使用条件下,评估皮肤随时间推移的可见改善情况。

Study design elements included:

研究设计要素包括:

Evaluation of a high‑concentration tetrahexyldecyl ascorbate (THD ascorbate) formulation

高浓度四己基癸基抗坏血酸(THD抗坏血酸)配方的评估

Preclinical, ex vivo and randomized, double‑blind human clinical evaluations

临床前、体外和随机、双盲的人体临床评估

Adult subjects using the study product within a defined skincare regimen

在规定护肤程序中使用研究产品的成年受试者

Multiple assessment visits to evaluate changes from baseline

多次评估访问以评估自基线以来的变化

Investigator grading of visible skin attributes, including tone uniformity, radiance, texture and overall appearance

研究人员对可见皮肤属性的评分,包括肤色均匀度、光泽、纹理和整体外观

Advanced imaging technologies, including VISIA‑CR®, Primos 3D® and Antera 3D®, to support objective analysis

包括VISIA‑CR®、Primos 3D®和Antera 3D®在内的先进成像技术,以支持客观分析

Subject self‑assessment questionnaires measuring perceived cosmetic benefits and product experience

主题自我评估问卷,衡量感知的美容益处和产品体验

Monitoring of skin compatibility and cosmetic tolerability throughout the study period

整个研究期间对皮肤相容性和化妆品耐受性的监测

The study endpoints align with standardized cosmetic dermatology evaluation practices and reflect typical consumer use patterns.

研究终点与标准化的化妆品皮肤病学评估实践一致,并反映了典型的消费者使用模式。

Peer‑Reviewed Publications

同行评审出版物

The full studies are available online via the

完整的研究报告可以在线获取,通过

Journal of Cosmetic Dermatology

化妆品皮肤病学杂志

:

A Closer Look at Penetration: The Efficacy Gap in Vitamin C Products

更深入地看渗透性:维生素C产品中的功效差距

Hydroquinone‑Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health

无氢醌、含四己基癸基抗坏血酸的抗氧化精华,用于色素沉着和光损伤肌肤,以实现肌肤健康。

About C+ Correcting Complex 30%®

关于C+ 矫正复合物 30%®

C+ Correcting Complex 30%® is Revision Skincare®'s highest‑strength vitamin C formulation. The product features THD ascorbate combined with complementary cosmetic ingredients, including patent‑pending MelaPATH® Technology, designed to support brighter‑looking skin, improved texture and a more even‑toned appearance.

C+ 矫正复合物 30%® 是 Revision Skincare® 浓度最高的维生素C配方。该产品采用THD抗坏血酸,结合了互补的化妆品成分,包括专利待批的MelaPATH®技术,旨在帮助提亮肤色、改善肤质,并使肤色更加均匀。

You can purchaseC+ Correcting Complex 30%® at .

您可以购买C+ 矫正复合物 30%® 。

revisionskincare.com

修订护肤网

or through an authorized seller.

或通过授权卖家。

About Revision Skincare

关于Revision护肤

®

®

Revision Skincare

修丽可护肤

®

®

** is redefining professional results by targeting skin longevity at its source. As the only brand formulating specifically for the Dermal‑Epidermal Junction (D•E•J) — known as the Longevity Layer™ — Revision Skincare addresses visible signs of aging by strengthening the skin's biological foundation.

** 正在通过针对皮肤长寿的根源重新定义专业成果。作为唯一一个专门针对真皮-表皮交界处(D•E•J)——即所谓的长寿层™——进行配方设计的品牌,Revision Skincare 通过增强皮肤的生物学基础来应对可见的衰老迹象。

For more than 20 years, the company has paired patented, medical‑grade innovations with a philosophy rooted in respecting skin's natural biology without disrupting the microbiome. Backed by physician‑validated clinical testing, Revision Skincare delivers bioavailable solutions that support long‑term skin health and visible results..

二十多年来,该公司将获得专利的医用级创新技术与尊重皮肤自然生物学特性且不破坏微生物组的理念相结合。经过医生验证的临床测试,Revision Skincare 提供生物可利用的解决方案,支持长期皮肤健康并呈现显著效果。

For more information, visit

欲了解更多信息,请访问

www.revisionskincare.com

www.revisionskincare.com

.

Contact: Revision Skincare®, Media Relations,

联系人:Revision Skincare®,媒体关系,

[email protected]

电子邮件地址

,

www.revisionskincare.com

www.revisionskincare.com

SOURCE Revision Skincare

源代码修订护肤品

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