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泰国医学研究人员揭示光生物调节疗法在老龄化口腔健康方面的突破

Thailand Medical Researchers Reveal Photobiomodulation Therapy Breakthrough for Aging Oral Health

Thailand Medical News 等信源发布 2026-04-14 18:19

可切换为仅中文


Thailand Medical

泰国医学

: A new systematic review by Thailand Medical researchers is drawing attention to a promising, non-invasive treatment that could transform how oral health issues are managed in older adults. The therapy, known as photobiomodulation therapy (PBMT), uses low-level light to reduce pain, speed healing, and control inflammation - offering new hope for millions suffering from age-related oral conditions..

泰国医学研究人员的一项新系统综述引起了人们对一种有前景的非侵入性治疗的关注,这项治疗可能会改变老年人口腔健康问题的管理方式。这种疗法被称为光生物调节疗法(PBMT),利用低强度光减轻疼痛、加速愈合和控制炎症,为数百万受年龄相关口腔疾病困扰的人带来了新希望。

New laser therapy shows powerful benefits in reducing pain and improving oral health in older adults

新型激光治疗在减轻老年人疼痛和改善口腔健康方面显示出强大的益处。

Understanding the Growing Oral Health Challenge in Older Adults

了解老年人日益增长的口腔健康挑战

As people age, the mouth undergoes significant changes. The oral lining becomes thinner, healing slows down, and saliva production often drops. These changes increase the risk of painful conditions such as oral ulcers, burning mouth syndrome, dry mouth, and complications from cancer treatments. For many older individuals, these issues severely affect eating, speaking, and overall quality of life..

随着年龄的增长,口腔会发生显著变化。口腔黏膜变薄,愈合速度减慢,唾液分泌也常常减少。这些变化增加了诸如口腔溃疡、灼口综合征、口干以及癌症治疗并发症等痛苦状况的风险。对于许多老年人来说,这些问题严重影响了他们的进食、说话和整体生活质量。

Recognizing this growing problem,

认识到这一日益严重的问题,

Thailand Medical

泰国医学

researchers from the Faculty of Dentistry, Chiang Mai University, Thailand, and the School of Dentistry, University of Phayao, Thailand, conducted a comprehensive review of clinical trials to evaluate whether PBMT could offer real benefits.

泰国清迈大学牙医学院和泰国帕尧大学牙科学院的研究人员对临床试验进行了全面审查,以评估PBMT是否能带来真正的益处。

What the Study Analyzed

研究分析的内容

The research team reviewed 23 randomized controlled trials conducted between 2000 and 2025, focusing on patients aged 60 and above. These studies examined PBMT across a wide range of oral conditions, including cancer therapy-related mouth damage, burning sensations, dry mouth, post-surgical pain, and dental implant healing..

研究团队回顾了2000年至2025年间进行的23项随机对照试验,重点关注60岁及以上的患者。这些研究检查了PBMT在广泛的口腔疾病中的应用,包括与癌症治疗相关的口腔损伤、灼烧感、口干、术后疼痛以及种植牙愈合等问题。

The findings were compelling. According to the data analyzed in the study, PBMT consistently demonstrated strong clinical benefits, particularly in managing oral mucositis - a painful condition commonly seen in cancer patients undergoing radiation or chemotherapy.

研究结果令人信服。根据研究中分析的数据,PBMT始终显示出强大的临床益处,特别是在治疗口腔黏膜炎方面——这是一种在接受放疗或化疗的癌症患者中常见的痛苦症状。

Strong Evidence for Cancer-Related Oral Damage

强证据表明癌症相关的口腔损伤

Among all conditions studied, the most convincing results were seen in patients with cancer therapy-induced oral mucositis. PBMT significantly reduced pain, delayed the onset of mouth sores, and decreased their severity. Patients also reported better quality of life and required fewer pain medications..

在所有研究的条件中,癌症治疗引起的口腔黏膜炎患者中观察到了最令人信服的结果。PBMT显著减轻了疼痛,延缓了口腔溃疡的发生,并降低了其严重程度。患者还报告了更好的生活质量,并且需要更少的止痛药。

In some trials, up to 83 percent of patients receiving PBMT showed no oral soreness after treatment, compared to much lower recovery rates in control groups. This highlights the therapy’s potential as a supportive treatment during cancer care.

在一些试验中,接受PBMT治疗的患者中多达83%在治疗后没有口腔疼痛,相比之下,对照组的恢复率则低得多。这突显了该疗法作为癌症护理期间支持性治疗的潜力。

Mixed but Promising Results for Other Conditions

其他条件下的结果混杂但前景乐观

For burning mouth syndrome - a condition causing chronic burning sensations - PBMT showed noticeable improvements in pain levels. However, some studies also found similar improvements in placebo groups, suggesting a psychological component may influence results.

对于灼口综合征(一种导致慢性灼烧感的疾病),PBMT显示出在疼痛水平上有显著改善。然而,一些研究也发现安慰剂组有类似的改善,表明心理因素可能会影响结果。

In cases of dry mouth, PBMT helped increase saliva production, which is crucial for digestion, speech, and preventing i

在口干的情况下,PBMT有助于增加唾液分泌,这对消化、说话和预防至关重要。

nfections. Meanwhile, patients undergoing dental implant procedures showed modest improvements in healing and tissue stability when PBMT was used.

感染。同时,接受牙种植手术的患者在使用PBMT时,其愈合和组织稳定性显示出适度的改善。

For postoperative pain, results were more limited but still encouraging, particularly in reducing pain during the first 24 hours after surgery.

术后疼痛方面,结果较为有限但仍令人鼓舞,尤其是在减少术后头24小时内的疼痛方面。

Safety Profile Stands Out

安全性表现突出

One of the most striking findings of the review is the safety of PBMT. Across all 23 trials, no serious side effects were reported. Some patients experienced mild warmth during treatment, but this did not require any medical intervention. This makes PBMT especially appealing for older adults who may already be managing multiple medications and health conditions..

审查中最显著的发现之一是PBMT的安全性。在所有23项试验中,没有报告严重的副作用。一些患者在治疗过程中感到轻微的温暖,但不需要任何医疗干预。这使得PBMT对可能已经在管理多种药物和健康状况的老年人特别有吸引力。

This

Medical News

医学新闻

report highlights that while PBMT is not yet a universal solution, it is rapidly gaining recognition as a valuable adjunct therapy in dentistry, especially for aging populations.

报告强调,虽然PBMT还不是一种通用的解决方案,但它正在迅速获得认可,成为牙科领域中一种有价值的辅助疗法,特别是对于老龄化人群。

Need for Standardization and Further Research

标准化和进一步研究的必要性

Despite the positive outcomes, researchers emphasized that treatment protocols varied widely across studies. Differences in light wavelength, dosage, and treatment duration make it difficult to establish a single standardized approach. More high-quality clinical trials are needed to determine optimal treatment settings and long-term benefits..

尽管结果积极,但研究人员强调,不同研究中的治疗方案差异很大。光波长、剂量和治疗持续时间的不同使得很难建立一个单一的标准化方法。需要更多高质量的临床试验来确定最佳的治疗设置和长期效益。

Conclusion

结论

Photobiomodulation therapy is emerging as a safe, effective, and patient-friendly option for managing a wide range of oral health problems in older adults. Its strongest impact is seen in reducing the severity and pain of cancer-related oral complications, while also showing promise in improving dry mouth and burning sensations.

光生物调节疗法正成为一种安全、有效且患者友好的选择,用于管理老年人广泛的口腔健康问题。其最显著的效果体现在减轻癌症相关口腔并发症的严重程度和疼痛,同时在改善口干和灼烧感方面也显示出希望。

Although more research is needed to refine treatment protocols, the current evidence strongly supports integrating PBMT into geriatric dental care..

尽管需要更多的研究来完善治疗方案,但目前的证据强烈支持将PBMT整合到老年牙科护理中。

With no significant side effects and meaningful clinical benefits, this therapy could soon become a standard part of oral healthcare for aging populations worldwide.

由于没有显著的副作用且具有重要的临床益处,这种疗法可能很快成为全球老龄化人口口腔护理的标准部分。

The study findings were published in the peer reviewed Dentistry Journal.

研究结果发表在经同行评议的《牙科学杂志》上。

https://www.mdpi.com/2304-6767/14/4/231

https://www.mdpi.com/2304-6767/14/4/231

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