Almanac Health Raises $10 Million to Empower Clinicians Across Specialties with Safe, Research-Validated Clinical AI

Almanac Health筹集1000万美元，以安全、经过研究验证的临床AI赋能各专科医生

Seed round led by F-Prime, with participation from General Catalyst and Lightspeed Venture Partners. General Catalyst previously led the pre-seed round.

种子轮融资由F-Prime领投，General Catalyst和Lightspeed Venture Partners参投。General Catalyst此前领投了前种子轮融资。

BOSTON, April 23, 2026-- Almanac Health, a research-validated clinical AI platform and evidence-based clinical decision support company founded by physician-researcher Cyril Zakka, MD, whose work at Stanford introduced retrieval-augmented generation to clinical medicine, has raised $10 million in a seed round led by F-Prime, with participation from General Catalyst and Lightspeed Venture Partners.

波士顿，2026年4月23日——Almanac Health是一家经过研究验证的临床人工智能平台和基于证据的临床决策支持公司，由医生研究员Cyril Zakka创立，其在斯坦福大学的研究首次将检索增强生成技术引入临床医学。该公司在F-Prime领投的种子轮融资中筹集了1000万美元，General Catalyst和Lightspeed Venture Partners也参与了投资。

General Catalyst previously led the company’s pre-seed round with participation from Soma Capital. This financing brings Almanac Health’s total funding to nearly $12 million and will accelerate the company’s mission to bring safe, evidence-grounded AI to clinicians and health systems..

General Catalyst 此前领投了该公司的 pre-seed 轮融资，Soma Capital 也参与其中。此次融资使 Almanac Health 的总融资额接近 1200 万美元，将加速公司为临床医生和医疗系统提供安全、基于证据的 AI 的使命。

Almanac Health is a unified clinical AI platform for clinical decision support that brings specialist-grade knowledge to every clinician at the point of care. It is designed to work within existing electronic health record (EHR) systems, governed by institutional controls, and grounded in peer-reviewed evidence.

Almanac Health 是一个统一的临床人工智能平台，用于临床决策支持，为每位临床医生在诊疗过程中提供专家级的知识。该平台旨在与现有的电子健康记录（EHR）系统协同工作，受机构控制管理，并基于经过同行评审的证据。

The platform is currently undergoing rigorous clinical validation in academic medical center settings..

该平台目前正在学术医疗中心进行严格的临床验证。

“There is no shortage of technologies promising to transform medicine. But few are grounded in real evidence, built with integrity and deserving of trust from the people and organizations using them. Almanac Health’s goal is to build clinical AI held to that standard. Validated through research, with incentives aligned with clinicians and patients.

“从不缺乏承诺要改变医疗的技术，但很少有技术是基于真实证据、以诚信构建并值得使用它们的个人和组织信赖的。Almanac Health 的目标是建立符合这一标准的临床人工智能。通过研究验证，并与临床医生和患者的激励措施保持一致。”

We’re focused on getting that right,” said Cyril Zakka, MD, founder and CEO of Almanac Health..

“我们正专注于把它做好，”Almanac Health的创始人兼首席执行官Cyril Zakka医学博士说。

Cyril Zakka, MD has worked at the intersection of medicine and AI across clinical practice, academic research, and industry. After earning his MD, he went on to conduct machine learning research at Stanford, where he developed the first retrieval-augmented generation system for clinical medicine, an approach to grounding AI in trusted medical knowledge that has since been widely adopted across clinical AI.

Cyril Zakka医学博士在临床实践、学术研究和行业领域中，致力于医学与人工智能的交叉工作。在获得医学博士学位后，他在斯坦福大学进行了机器学习研究，开发了首个用于临床医学的检索增强生成系统，这是一种将人工智能立足于可信医学知识的方法，此后已在临床人工智能领域得到广泛采用。

That work, published in NEJM AI, became one of the journal’s most-cited papers and established the foundational approach used by most clinical evidence AI products today. He subsequently led health AI at Hugging Face, the largest open-source AI platform, before founding Almanac Health..

这项发表在《新英格兰医学杂志》AI特刊上的工作成为了该期刊被引用最多的论文之一，并奠定了当今大多数临床证据AI产品所使用的基础方法。之后，他在创立Almanac Health之前，领导了最大的开源AI平台Hugging Face的健康AI部门。

“Cyril is one of the rare founders who has both the clinical training and the technical depth to build AI that clinicians will actually trust as well as the discipline to validate it before deploying it. Almanac Health represents what we believe the next generation of healthcare AI should look like: grounded in research, governed by institutions, and built with incentives that put clinicians and patients first,” said Carl Byers, Partner at F-Prime..

“西里尔是少数拥有临床培训和技术深度的创始人之一，他能够构建出临床医生真正信任的人工智能，并且在部署之前有严谨的态度去验证它。Almanac Health 代表了我们认为下一代医疗人工智能应有的样子：以研究为基础，由机构管理，并以将临床医生和患者放在首位的激励机制来构建。” F-Prime 合伙人卡尔·拜尔斯表示。

The funding will allow the company to grow its team across clinical medicine, AI research, and health systems infrastructure, as well as advance R&D with a focus on privacy, reliability, and rigorous evaluation before deployment.

这笔资金将使该公司能够在其临床医学、人工智能研究和卫生系统基础设施等领域发展团队，并在部署前推进专注于隐私、可靠性和严格评估的研发工作。

“We believe the next generation of healthcare infrastructure will be defined by how effectively it translates frontier intelligence into everyday clinical decisions. Almanac is doing exactly that: building a physician-centric platform that brings trusted, evidence-based intelligence into the workflow, with the alignment and accountability required for true health assurance,” said Alexandre Momeni, Partner at General Catalyst..

“我们相信，下一代医疗基础设施将取决于它如何有效地将前沿智能转化为日常临床决策。Almanac 正在做的是：构建一个以医生为中心的平台，将可信的、基于证据的智能带入工作流程，并具备实现真正健康保障所需的协调性和责任感，”General Catalyst 的合伙人亚历山大·莫梅尼表示。

Almanac Health is hiring across engineering, AI research, and clinical development. Interested candidates can contact cyril@almanac.chat or visit https://almanac.chat/.

Almanac Health 正在工程、人工智能研究和临床开发领域招聘。有兴趣的候选人可以联系 cyril@almanac.chat 或访问 https://almanac.chat/。

Clinicians and health system leaders interested in early access to Almanac Health can reach the team at support@almanac.chat.

有兴趣提前使用Almanac Health的临床医生和卫生系统负责人可以通过support@almanac.chat联系团队。

About Almanac Health

关于年鉴健康

Almanac Health is a clinical AI platform that brings specialist-grade knowledge to clinicians at the point of care, providing evidence-based clinical decision support across medical specialties, free from pharmaceutical advertising, and governed by institutional controls. The platform integrates with existing EHR systems and is clinically validated through peer-reviewed research.

Almanac Health 是一个临床人工智能平台，为医护人员在诊疗过程中提供专业级别的知识支持，覆盖各医学专科的循证临床决策辅助，无药物广告干扰，并受机构管控。该平台与现有的电子健康记录（EHR）系统集成，且通过同行评审研究进行临床验证。

Almanac Health was founded by Cyril Zakka, MD, author of one of NEJM AI’s most-cited papers on retrieval-augmented generation for clinical medicine, and is backed by F-Prime, General Catalyst, and Lightspeed Venture Partners. For more information, visit https://almanac.chat/..

Almanac Health 由 Cyril Zakka 医学博士创立，他是《新英格兰医学杂志》人工智能上关于检索增强生成在临床医学领域应用的最多引用论文之一的作者，并受到 F-Prime、General Catalyst 和 Lightspeed Venture Partners 的支持。欲了解更多信息，请访问 https://almanac.chat/。

Contact:

联系：

Media Contact: press@almanac.chat

媒体联系：press@almanac.chat