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Researchers have developed a method for genetic barcoding and lineage tracing in sheep using CRISPR/Cas9 technology, according to findings published on April 24, 2026. The study outlines how this approach enables precise tracking of cell lineages in sheep, providing insights into developmental biology and disease progression.

研究人员开发了一种利用CRISPR/Cas9技术对绵羊进行基因条形码标记和谱系追踪的方法，该研究成果于2026年4月24日发表。研究表明，这种方法能够精确追踪绵羊的细胞谱系，为发育生物学和疾病进展提供了深入见解。

The technique utilizes CRISPR/Cas9-induced edits to introduce unique genetic markers, or “barcodes,” into the DNA of individual cells..

该技术利用CRISPR/Cas9诱导的编辑，在单个细胞的DNA中引入独特的遗传标记，或称为“条形码”。

The research team demonstrated that these genetic barcodes can be used to trace cellular origins and differentiation pathways over time. By applying this method in sheep models, scientists were able to monitor how specific cell populations evolved during development or responded to experimental conditions.

研究团队展示了这些基因条形码可以用来追踪细胞的起源和分化路径。通过在绵羊模型中应用这种方法，科学家能够监测特定细胞群体在发育过程中或对实验条件的反应如何演变。

The study highlights the potential applications of this technique for understanding complex biological processes and improving animal models for biomedical research. Further details about the methodology and findings are available in the publication linked above..

该研究强调了这种技术在理解复杂生物过程和改进用于生物医学研究的动物模型方面的潜在应用。有关方法和结果的更多细节，请参阅上面链接的出版物。

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Source: GO-AI-ne1

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Date: April 24, 2026

日期：2026年4月24日

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