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神经系统疾病疗法开发商Autonomix临床前研究成功证明神经消融可以减缓癌症胰腺癌的转移

Autonomix Preclinical Study Successfully Demonstrates That Nerve Ablation Can Slow Tumor Metastasis in Pancreatic Cancer

GlobeNewswire 2024-05-23 21:15 翻译由动脉网AI生成,点击反馈

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Results from the preclinical study demonstrated statistically significant reduction of metastases and statistically significant reduction in tumor mass Lori Bisson, Chief Executive Officer discusses the animal study in a Virtual Investor “What This Means” segment here THE WOODLANDS, TX, May 23, 2024 (GLOBE NEWSWIRE) -- Autonomix Medical, Inc.

临床前研究的结果显示,转移灶的统计学显着减少,肿瘤质量的统计学显着减少首席执行官Lori Bisson在虚拟投资者“这意味着什么”部分中讨论了动物研究,德克萨斯州伍德兰兹,2024年5月23日(环球通讯社)-Autonomix Medical,Inc。

(NASDAQ: AMIX) (“Autonomix” or the “Company”), a medical device company focused on advancing innovative technologies to revolutionize how diseases involving the nervous system are diagnosed and treated, today announced the successful completion of an animal study evaluating the ability of targeted nerve ablation to impact tumor metastases and growth.

(纳斯达克:AMIX)(“Autonomix”或“公司”)是一家专注于推进创新技术以彻底改变涉及神经系统疾病的诊断和治疗方式的医疗器械公司,今天宣布成功完成一项动物研究,评估靶向神经消融影响肿瘤转移和生长的能力。

For the preclinical mouse study, two groups of mice received human pancreatic tumor cells (Mia PaCa2) into the pancreatic head region. The experimental group received peri-pancreatic neural ablation (ethanol infusion over the pancreatic nerves) while the control group received no treatment. Results of the experimental group demonstrated a statistically significant reduction of the tumor mass growth and metastases.

对于临床前小鼠研究,两组小鼠在胰头区域接受人胰腺肿瘤细胞(Mia PaCa2)。实验组接受胰周神经消融(胰神经灌注乙醇),而对照组不接受治疗。实验组的结果显示肿瘤质量生长和转移的统计学显着减少。

Local invasion showed a 60% difference between the control and experimental group while liver metastases showed a 40% difference. Lori Bisson, Chief Executive Officer of Autonomix, commented, “The successful completion of this preclinical animal study and highly encouraging results, support the clinical literature suggesting that nerve fibers may be a pathway for cancer cell metastasis tumor growth.

局部浸润显示对照组和实验组之间有60%的差异,而肝转移显示出40%的差异。Autonomix首席执行官Lori Bisson评论道:“这项临床前动物研究的成功完成和令人鼓舞的结果支持了临床文献,表明神经纤维可能是癌细胞转移肿瘤生长的途径。

The results further support the concept that neural pathways are especially impactful in the pathogenesis of pancreatic cancer. Even with a small sample size in this preclinical study, the experimental group demonstrated statistically significant metastasis reduction. While our.

结果进一步支持了神经通路在胰腺癌发病机制中特别重要的概念。即使在这项临床前研究中样本量很小,实验组也显示出统计学上显着的转移减少。而我们。

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