Dynamic Therapeutics, a spin-out from the University of Bristol, has been awarded a Blavatnik Prize from venture capital firm QantX, for its pioneering U-RHYTHM technology, which can capture up to 72 samples over 24 hours with data on hormone production.The U-RHYTHM technology measures the patterns of biologically active molecules in the tissues and identifies how they change over time.

英国布里斯托尔大学（University of Bristol）推出的动态疗法（Dynamic Therapeutics）因其开创性的U型节律技术而获得风险投资公司QantX颁发的Blavatnik奖，该技术可以在24小时内采集多达72个样本，并提供激素产生的数据。U节律技术测量组织中生物活性分子的模式，并确定它们如何随时间变化。

The data generated can then be analysed to identify potential disruptions which could impact health. Importantly it can also detect these disruptions at the earliest stage.Conventional techniques for diagnosing and managing hormone-related disorders can be complicated. Typically, hormone levels vary greatly across the day and in individual patients, and traditionally a single measurement would usually be taken in the morning.The goal of Dynamic Therapeutics is to become the gold standard for time-based measurement of hormones to improve accuracy of diagnoses and treatment for patients with conditions like Type 1 diabetes and hypertension.The technology has a range of potential uses including: more accurate time-based monitoring of fertility levels; monitoring metabolites and infection in post-operative care; monitoring drug concentration levels and effectiveness in drug development; and an an alternative to blood sampling in neonates and young children.Richard Haycock, CEO at QantX, said: “We know more than ever about the workings of the human body and yet the diagnosis and treatment of many conditions remain challenging, particularly those caused by hormonal imbalances which vary with time.“Whilst clinicians rely on single point-in-time tests such as blood and urine, the U-RHYTHM device has the potential to capture dynamic information about a patient’s health and improve diagnosis.

然后可以分析产生的数据，以确定可能影响健康的潜在中断。重要的是，它还可以在最早的阶段检测到这些中断。诊断和管理激素相关疾病的常规技术可能很复杂。通常，激素水平在一天中和个体患者中差异很大，传统上通常在早上进行一次测量。动态疗法的目标是成为基于时间的激素测量的金标准，以提高1型糖尿病和高血压等疾病患者的诊断和治疗准确性。这项技术有一系列潜在的用途，包括：更准确的基于时间的生育水平监测；监测术后护理中的代谢物和感染；监测药物浓度水平和药物开发的有效性；以及新生儿和幼儿血液采样的替代方法。QantX首席执行官理查德·海考克（Richard Haycock）表示：“我们比以往任何时候都更了解人体的工作原理，但许多疾病的诊断和治疗仍然具有挑战性，特别是那些由激素失衡引起的疾病，这些疾病随时间而变化。”虽然临床医生依赖于血液和尿液等单点时间测试，但U型节律设备有可能捕捉患者健康的动态信息并改善诊断。

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